Clinical Variant Analysis with Qiagen Clinical Insight (QCI)
The QCI Interpret platform is a software platform developed for clinical genetic testing and biomarker analysis. This tool is designed to assist healthcare professionals in interpreting genetic data, reporting, and clinical decision-making processes. It is commonly used in the evaluation of data related to cancer, hereditary diseases, and other genetic conditions. QCI Interpret provides a […]
NGS (Next-Generation Sequencing) Analysis (Secondary Analysis) with CLC Genomics Workbench
CLC Genomics Workbench is a powerful bioinformatics software platform used for the analysis of genetic and genomic data. It is designed to process large-scale NGS (Next-Generation Sequencing) data, align sequences with high accuracy, and perform analyses with high sensitivity. The platform provides comprehensive data processing tools for genome, transcriptome, metagenome, and epigenome analyses. With its […]
Access to and Integration with Robust Clinical Databases
COSMIC (Catalogue of Somatic Mutations in Cancer): A comprehensive database focused on somatic mutations associated with cancer. It serves as a valuable resource, particularly for scientists working in the field of cancer genetics and biology. HGMD (Human Gene Mutation Database): A database that compiles mutations found in human genes and their associations with diseases. It […]
Ingenuity Pathway Analysis (IPA)
Ingenuity Pathway Analysis (IPA) is a software used for the analysis and interpretation of biological data. It is particularly utilized in the examination of genetic, protein, and metabolic data. IPA provides an integrated platform to associate data with biological pathways, cellular processes, and diseases. This tool helps researchers analyze datasets, model biological pathways, and understand […]
HLA-B27
HLA-B27 is a genetic marker protein in our body and is associated with immune system-related diseases. The most common diseases linked to the HLA-B27 gene include ankylosing spondylitis, reactive arthritis, psoriatic arthritis, enteropathic arthritis, and uveitis.
HLA-B57
It is another genetic marker that affects the immune system. It is particularly focused on its connection with drug reactions and certain infections. Abacavir allergy, autoimmune diseases, and the treatment of chronic viral infections are influenced by this genetic marker.
HLA Celiac Disease
Celiac Disease is an autoimmune condition that arises from a genetic predisposition and is characterized by an abnormal immune response to gluten. The genetic risk for celiac disease is determined by the HLA-DQ2 and HLA-DQ8 genetic structures.
HLA-A29
It is another genetic marker associated with the immune system and is linked to a predisposition for certain autoimmune diseases. Its most common association is with a condition called Birdshot Chorioretinopathy.
HLA-Behçet’s Disease
Behçet’s Disease is a chronic autoinflammatory condition characterized by symptoms such as sores in the mouth and genital areas, skin lesions, and eye inflammation. While the exact cause of the disease is unknown, it is believed to arise from a combination of genetic and environmental factors.
HLA-Narcolepsy
HLA-Narcolepsy is particularly associated with the HLA-DQB1*06:02 genetic marker. Narcolepsy is a neurological disorder where the mechanisms regulating sleep are disrupted, and the HLA genetic structure suggests that this disorder may have an autoimmune origin.
HLA-C*06 Psoriasis
HLA-C*06 is an HLA subgroup strongly associated with psoriasis. This genetic variant is related to the immune system and may increase the risk of developing psoriasis. However, the presence of this gene does not necessarily mean that the disease will develop.
HLA Diabetes Mellitus T1
HLA and Type 1 Diabetes is a condition in which genetic factors, particularly those related to the immune system, play a role. Type 1 diabetes occurs when the insulin-producing beta cells in the pancreas are destroyed by the immune system. In this process, certain HLA genes have been associated with susceptibility to the disease.
LIFECODES KIR Typing Kit
NGSgo-AmpX KIR Typing
Chimerism Monitoring Software
NGS-Based Chimerism
Digital PCR-Based Chimerism
RT-PCR-Based Chimerism
Sanger Sequencing-Based HLA Typing
DSA (Donor-Specific Antibody) Detection Kit
Donor-Specific Antibodies (DSA) have been shown to play a role in both chronic and acute rejection of transplanted allografts. It provides superior solutions for DSA detection in transplant samples. DSA testing enables the screening of antibodies developed against the donor’s HLA antigens. It is ideal for pre- and post-transplant testing.
LSA-MIC Kit
The LSA-MIC kit is designed to detect antibodies developed against MICA antigens. Recent studies suggest that anti-MICA antibodies may play a role in kidney transplant failure. To ensure high coverage at well-known MICA polymorphic amino acid positions, the majority of selected MICA antigens are included in the panel. Most immunogenic epitopes are present in multiple […]
